Oh, a Diablo or Borderlands like game where the items (loot) and their effects are AI generated.
I don't think we're at a point where this is possible yet. But I'd love to see the kind of random stuff the AI could come up with.
That would also mean: no more meta builds. You'd have to come up with your own build based on the unique items you got.
https://xkcd.com/927