Both drives were encrypted (Samsung as root drive, encrypted except for the efi partition, and kioxia fully encrypted and mounted via crypttab and a key file residing on the encrypted Samsung partition for automatic unlock), although now as I have been reinstalling quite often, and couldn't be bothered to set up the encryption for the second drive so it stays unused atm. Trim is enabled via a kernel parameter, but not in the fstab directly anymore (as I'm running BTRFS now, and from what I've gathered passing the ssd option to BTRFS is enough to enable trim, verified with lsblk --discard)
I did, yes. One of the first ideas I got.