Drawing Sonic like this is extremely inappropriate...

Draw the mono-eye or DON'T DRAW HIM AT ALL.

This would be a good thing, though I think it's trickier than it appears:

• How arbitrary are "best before" and "expires on" labels and how do they differ from food to food?
• How do the labels themselves differ from each other and how to do they differ from jurisdiction to jurisdiction?
• Could acknowledging that "expired" food is still good cause expiry dates to just be extended? How far could they be extended before food actually is dangerous past the label?
• How does liability work when someone gets sick from "expired" food? Does it change when it's part of a structured donation system?

Isn't this a strange article title? The whole point of it is to show T cells don't actually get "burned out" at all. And imo it's not like the real reason is uninteresting.

Why dress the article in the exact thing it's refuting?

Kbin does that in terms of function as in kbin has its own microblogging element to the experience, but it doesn't do anything to bring the existing kbin and mastodon universes together.

Mastodon can do this. Mastodon interprets Lemmy communities as users, Lemmy threads as boosted posts with user mentions, and Lemmy comments as replies. If you search on Mastodon for a Lemmy community using the Mastodon format e.g. @community@domain instead of !community@domain you'll find the community and posts.

There's nothing wrong with being right all the time, but relationships need more than just the exchange of facts. If all people know you for is the guy who is right all the time (or needs to be right all the time), then maybe you're neglecting the other aspects of those relationships. There needs to be other things people remember you for.

Are you calling the server list on joinmastodon.org "the federation"? Because it's not; it's literally just a list. Nothing about the list tells you about any actual federation between instances. Without a doubt there are instances on that list that are federated with ones not on that list and vice versa. It's not even the only list out there.

This is extremely valuable, thanks for this!

As a general question, why did you decide to use a single postgres container for multiple services instead of multiple, stack specific containers? When I first started working with containers I considered your scheme for the sake of minimalism, but didn't want a single container to bring down multiple unrelated services. I also had the resources to accomodate the redundancy.

Lots of comments already telling you to stay home so I don't think I need to. What I will say is if you don't want to contribute to the growing number of variants, you'll stay home. Variants largely arise from mutations in the virus during replication. Humans are virus-replication machines. If you're infected you could be carrying a new variant right now and the only way to stop it is to let it die inside you. Your body's immune system will already be in full swing and be in the best position to deal with it as opposed to an uninfected person.

Don't contribute to the endemicity of COVID.

The Proton free tier is pretty limited compared to Gmail, in particular for me, you're only allowed 1 label. The basic paid tier opens up a lot more. They definitely want you to upgrade to the paid tier.

At the beginning of the pandemic I looked into ways to de-Google and found Nextcloud. It wasn't the easiest thing to start with, especially for a novice, but I had the time and the hardware, and I'm the type to not mind jumping into something difficult if it means solving a specific problem. I then found out about Bitwarden and had a great experience setting that up. After that I was confident enough to try hosting anything I could find. It's been good times ever since 😀

What was the surgery for?

This will be a terrible answer to your question, but I recently listened to this episode of the Linux Unplugged podcast and they seem try to explain the situation from Red Hat's perspective. It sounds very technical, but it was interesting to listen to because up until then I had only been seeing anti Red Hat commentary online.

The sign-in experience is where you're going to get a lot of friction. Your users are going to need your server address. They'll have to log in to devices with username/password including TVs unless they have signed in once already somewhere else on the network like a desktop. Then you can set up an Easy PIN code or use Quick Connect, but those are hidden behind the user settings menu.

Is this a repost? I've seen this exact same post somewhere.

Anyway, SimpleX may not be decentralized OOTB, but can be made to be since their relays are self-hostable. It should be as simple as spinning up an instance and changing the url in app.

Do you have any rationale behind keeping in touch with those people in spite of their treatment of you? What do you believe about their future behaviour?

If you're talking about this, then it hasn't seen an update since 2021. Maybe you mean Finamp? It's a serviceable app, but it's very simple and dated-looking compared to Plexamp. Definitely better than the Jellyfin app though which is just a web wrapper.

This is a simplistic, yet common take. Privacy is not a zero-sum game. If it was, entities that valued your information wouldn't construct systems to constantly scrape it from you.

As long as you engage with society you will always be generating new information, even it's as basic as confirming that old information is still correct. That means it's never too late to adopt privacy practices.

Joined on one instance, it went away, had to create a new account on this instance.

That's a really annoying issue. Not being able to trust an instance to keep your account alive plants the seeds for a centralization problem in the future.

Are you still using it? I went through many deployments before I finally thought I had it settled.

Agreed, though I think it's less "we don't want you here" and more "you're on your own". I liken it to Linux in that sense where new users are expected to try harder to learn the ins and outs. The difference is with Linux what you learn can be applied in so many more places in your Linux experience. With Lemmy, once you grasp the technical depth of it there's not much you can do with it except explain it to another person.

Except OP is starting a meta discussion about Reddit discussions, not a direct discussion about Reddit. I don't necessarily agree with OP, but you've crafted an artificial contradiction using a false equivalence. I'd be happier if we left the Reddit-tier logic back where it belongs.

Agreed. There's an option in Mastodon to hide replies in a feed which in theory could solve the problem, but it never hid anything for me. Maybe try that?

I need my GIF button

I agree, though I probably wouldn't call it marketing or advertising. Maybe just a better and more accessible introduction and onboarding experience.

100%

I would hope in the future we get a more fleshed out version of multireddits. I think it would be a decent solution since I don't think duplication of communities is a phenomenon that will ever go away.

IMO the title is incorrect because the common interpretation of getting "burned out" is that of the same individuals of a population losing effectiveness after working hard. The article even likens the term "exhausted" the same interpretation of the phrase:

Altogether, our research suggests that T cells in tumors are not necessarily working hard and getting exhausted. Rather, they are blocked right from the start.

This same quote describes the truth of the phenomenon where it's not individuals getting "exhausted", but cellular signalling permanently altering the expression of T cells to make them less and less effective.

A more correct title would be something like:

Cancer makes every generation of T cells worse than the last

Available on desktop device (Windows, MacOS, Linux), because decentralized network may cause high amount of cellular data usage when connecting with nodes.

It looks like SimpleX does have a desktop app, it's just via cli: https://github.com/simplex-chat/simplex-chat/tree/stable#zap-quick-installation-of-a-terminal-app

Feedback on what works lets businesses allocate resources to things that will get new/keep current customers and save in places that don't matter as much. It's the core principle of any business and everything else, while useful and important in its own way, is secondary.

Now whether or not it feels like businesses are acting on that feedback in a way that makes a difference is a whole other beast.