By that logic any depiction of any form of supremacy, or otherism as a concept, regardless of intent, is detrimental. So, homogeneity only? Commentary is an excuse? Critiquing about the problem is as bad as endorsing it?
It sounds like you're not mad at Fallout specifically, but one of the core tropes of literature as a genre, and basically the entire concept of social satire.
The Establishment clause has applied to state law since 1947.