The official docs for Toon Boom Harmony 22 seem to have a page on how to install under Linux (RHEL or CentOS 6 or 7).
https://docs.toonboom.com/help/harmony-22/advanced/installation/basic/linux/about-basic-installation-linux.html https://docs.toonboom.com/help/harmony-22/advanced/installation/basic/linux/install-on-linux.html
You may get it working under Mint but it won't be supported.
You may have to look at a virtual machine or just put up with Windows because you need this software.
These are updates that will come through the repo. See the release note that is referenced by phoronix.
https://www.debian.org/News/2023/20230722