Why does incest result in birth defects?

Delphia@lemmy.world to No Stupid Questions@lemmy.world – 113 points –

Just to be well and truly fuckin clear. I am not now nor have I ever been nor will I ever be contemplating shagging a family member.

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I am a carrier of CFTR mutations. If I knock up a random woman theres a 1 in 80000 chance of the child having cystic fibrosis. If I knock up my sister theres a 1 in 16 chance instead.

I'm being pedantic, but if you know you're a carrier (and don't know the carrier status of your sister) then it is 1 in 8

You are correct, and i did realize this some time after posting I'm just too lazy to edit it.