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The Picard Maneuver@lemmy.world to ADHD memes@lemmy.dbzer0.com – 1010 points –
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Eli5. Isn't it just microdosing amphetamine?

Yeah, more or less. Stimulants tend to have a contradictory calming and/or focusing effect on the ADHD brain. I don’t remember why exactly but it probably has to do with dopamine regulation, which our brains crave like a zombie does brains.

My diagnosis kind of explained why I can drink inordinate amounts of coffee or energy drinks (don’t do this) and sleep like a log 30min later lol

Some brain cells make dopamine to reinforce behaviors. Dopamine slots into receptor, you get that feeling of satisfaction. A protein in the brain cell wall vacuums up excess dopamine so it doesn't just flood the brain forever, constantly triggering the receptors.
ADHD brain cell dopamine vacuums are just always on max speed all the time.
Methylphenidate slows the vacuums down so the dopamine doesn't get sucked right back down, meaning it actually has a chance to reach the receptors and do its job.

It's not quite that our brains crave dopamine, it's that our brains are too good at tidying it up, kinda like someone following around behind you as you set the table, putting all the clean dinnerware straight into the dishwasher unused.