What makes gel capsules so expensive in comparison to other pills?

Mothra@mander.xyz to Asklemmy@lemmy.ml – 58 points –

Disclaimer: I'm in Australia and here vitamins must comply with certain regulations. Feel free to read about it: https://www.tga.gov.au/news/blog/how-are-vitamins-regulated-australia

I bought vitamin D the other day, and couldn't help but to notice the price differences, such as:

Brand A: $8 x 300 pills Brand B: $30, x 250 capsules Brand C: $40, x 300 capsules

All had the same amount of vitamin per dose (1000 u). They all had the AUST L label which means they undergo controls to ensure that they have what they claim to have, and that they are made under certain safety standards.

I also buy iron supplements but there is nowhere near this much difference between brands. The only obvious difference was the type of pill, the more expensive ones were gel capsules while the cheap ones were hard pills.

So, are gel capsules really that much better? Is the price difference justified? Are there other issues that could explain the price difference in terms of quality?

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Capsules are considered more advanced drug packaging because none of the drug dissolves in your mouth when you swallow capsules. Unlike pills, 100% of the drug goes straight to your stomach, so there's no variation in the drug dosage, and the patient won't complain if the drug is bitter.

Also because you can open the capsule and pour it into the glass of water, if you have trouble swallowing pills. Which defeats the first advantage, and you can simply order powdered drug instead of pills, but it won't come pre-packaged as pills so it will be more expensive.

None of that matters for vitamins, you generally need more than 1000% of the daily dose for it to become harmful, so each pill contains more than your body really needs, because there are no side effects, so you can buy a pill and lick it, chew it, crush it, and add it to your coffee, and it will still work just fine.

and lick it, chew it, crush it,

Boil it, mash it, stick it in a stew

Shrimp soup, shrimp stew, shrimp salad, shrimp and potatoes...

Twist it, pull it, bop it...

Buy it, use it, break it, fix it Trash it, change it, mail, upgrade it Charge it, point it, zoom it, press it Snap it, work it, quick, erase it Write it, cut it, paste it, save it Load it, check it, quick, rewrite it Plug it, play it, burn it, rip it Drag and drop it, zip, unzip it Lock it, fill it, curl it, find it View it, code it, jam, unlock it Surf it, scroll it, pose it, click it Cross it, crack it, twitch, update it Name it, read it, tune it, print it Scan it, send it, fax, rename it Touch it, bring it, pay it, watch it Turn it, leave it, stop, format it

Does it actually make a difference if it dissolves in your mouth? Everything ends up in your stomach eventually.

It doesn't matter for most drugs, as long as you can tolerate the taste. There is a gastric ulcers medicine that's basically a weapons-grade concentrate of chili pepper, eating it raw will cause most people to vomit. Some rare drugs react poorly with saliva, and there are also drugs which are designed to dissolve not in your stomach but in your intestines, but those are usually not capsules but thumb-sized pills with coating so thick you won't be able to chew through it.

That gastric ulcers one sounds like euthanasia

But it's all herbal and natural!

dried plants are no less effective in making you vomit than synthetic drugs

Coated pills are generally designed to bypass your stomach intact to be dissolved in your duodenum