Trans youth will no longer be prescribed puberty blockers, NHS England says

MicroWave@lemmy.world to World News@lemmy.world – 488 points –
Trans youth will no longer be prescribed puberty blockers, NHS England says
thepinknews.com

Trans youth will no longer be prescribed puberty blockers at NHS England gender identity clinics in a new “blow” to gender-affirming healthcare.

Puberty blockers are a type of medicine that prevent puberty from starting by blocking the hormones – like testosterone and oestrogen – that lead to puberty-related changes in the body. In the case of trans youth, this can delay unwanted physical changes like menstruation, breast growth, voice changes or facial hair growth.

On Tuesday (12 March), NHS England confirmed the medicine, which has been described as “life-saving” medical care for trans youth, will only be available to young people as part of clinical research trials.

The government described the move as a “landmark decision”, Sky News reported. It believed such a move is in the “best interests of the child”.

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God damn Tories. What do they know about “best interests of the child” that a doctor doesn't already know? Less than nothing is the answer.

If a young person is suffering from gender dysmorphia to the point of considering gender affirmation procedures, then I think it'd be in their best interest to not exacerbate that condition. Delaying the onset of puberty via puberty blockers until they're at the age where that can legally consent to such procedures isn't exactly novel.

Even if they eventually decide not to undergo those procedures, all you habr to do is take them off the blockers and they'd undergo puberty as normal. There's not all that much downside for an awful lot of upside for those in need.

What you fail to take into account is the pink haired lesbian man haters dragging kids into alleyways and stopping them from having puberty. This is a totally real thing. A child can't even walk to school without being accosted by pink haired lesbian man haters armed with syringes and a copy of a Dworkin book.

Even if they eventually decide not to undergo those procedures, all you habr to do is take them off the blockers and they'd undergo puberty as normal. There's not all that much downside for an awful lot of upside for those in need.

Is that actually true? Do those medications actually permanently prevent puberty after a certain point?

There are side effects last I looked, people like to pretend their aren’t, even fucking ibuprofen has side effects.

So idk, it depends on how bad maybe?

They have side effects. Permanent puberty block isn't one of them. We've had these drugs on the market since the '80s, and they treat more than just trans youth. We have a pretty good idea on how puberty progresses with them.

Yes, there are side effects. They vary depending on the length of treatment (generally patients are not allowed to stay on them indefinitely to mitigate this) and the medication used, but puberty blockers have been used for ~40 years now and we have a good understanding of the risks. GnRH agonists are the most common type of puberty blocker used today, and the typical side effects are:

  • Hot flashes
  • Gynecomastia
  • Fatigue
  • Weight gain
  • Decreased libido and erectile function

These side effects generally end once treatment stops, whether switching to hormone replacement therapy or stopping all gender-affirming treatment. These side effects are typical of low sex hormone levels in general, and are generally annoyances that can be managed rather than major risks that are likely to harm the patient long term. It's also worth noting that some of these are seen as neutral or even positive to some patients - e.g. patients who were assigned male at birth and are interested in feminizing treatment often consider gynecomastia and decreased erectile function as positive effects.

When puberty blockers are continued for longer periods of time, there are additional risks which grow with the duration of the treatment:

  • Reduced bone density, which can increase risk of or worsen osteoporosis
  • Metabolic issues, which can worsen weight gain or diabetes in particular
  • Having puberty delayed by any means tends to result in a child growing taller than they would otherwise

These risks are more serious, which is why puberty blockers are not prescribed indefinitely. For gender affirming treatment, puberty blockers are generally prescribed for up to two or three years, depending on local regulations and the patient's tolerance of the treatment. After this period, patients have the option of either continuing gender affirming treatment with hormone replacement therapy (so that they can experience a different puberty than the one typically associated with their birth sex), or stopping treatment and allowing puberty to run its course as usual.

It's also worth noting that puberty blockers are not considered in a vacuum - the risks are considered against the risk of allowing puberty to continue as usual. For children with gender dysphoria, puberty is often a severely traumatic experience. This can cause or worsen depression and suicidality, and can leave a transgender person with sexual characteristics they do not want and will have to treat later with riskier and/or more intense forms of treatment like surgery. The risks of puberty blockers are comparatively mild, which is part of why the side effects are regarded as safe for transgender patients.

Lastly, I'll also note that all of this treatment involves mental health professionals as well. While adults in some regions can choose to start gender affirming treatment on their own without needing a formal diagnosis, treatment for children requires much more work and dedication. Typically, a minor who wants to begin gender affirming treatment for gender dysphoria will need:

  • Consent from at least one parent
  • A diagnosis or letter of support from a mental health practitioner who's seen them as a patient
  • A doctor or endocrinologist who can prescribe the medications
  • Ongoing check-ups while they're undergoing treatment, to assess both their physical health (physical exams, blood work to check hormone levels and organ function) and mental health (sessions with a mental health practitioner to make sure that the treatment is actually benefiting their mental health and consistent with their identity)

No, barring some other condition, puberty resumes once you stop using puberty blockers. There are increasing risks of side effects when staying on puberty blockers for more than a couple years, so it's usually a temporary measure to give children with gender dysphoria more time to explore their identity without subjecting them to the irreversible effects of puberty yet. As a result, doctors won't allow a patient to stay on puberty blockers permanently (barring outliers where it would actually be safer to do so, e.g. because of cancer risk associated with sex hormones). There are two typical outcomes:

  1. The patient determines that they would like to transition medically, and will transition from puberty blockers to hormone replacement therapy according to their goals. This essentially allows them to replace the pubertal effects typically associated with their birth sex with something else depending on the regimen.
  2. The patient determines that they don't want to transition medically, and stops puberty blockers without starting hormone replacement therapy. At this point, puberty begins/resumes on its own as usual.

Even if they eventually decide not to undergo those procedures, all you habr to do is take them off the blockers and they'd undergo puberty as normal. There's not all that much downside for an awful lot of upside for those in need.

Oh, don't worry. Statistically, people who start puberty blockers almost always go on to receive hormone therapy as adults, so you don't really have to worry about people deciding not to continue. It's definitely* because of the medicine that they go on to do HRT, and not because the kids that are getting through the bullshit to actually start blockers are the kids who are almost 100% guaranteed to be trans. Don't think too hard and it'll all just go away.

Doctors can be manipulated to support an agenda, too.

They used to classify homosexuality as a mental disorder, for example.

They also used to recommend lobotomies as treatment for unruly wives.

Do you think there are no instances of doctors being manipulated or corrupt in the current day? They of course have a profit incentive to get as much business as possible. It's why you seen cosmetic surgeons lie through their teeth to manipulate vulnerable people into giving them money.

Doctors still have a lot more experience of what works than Conservative politicians do. And if you took "it must be impossible for any doctor ever to abuse this power for corrupt ends" as the standard for approving a treatment, no treatments would ever get approved.

Doctors can be thrown in jail for supporting unnecessary care. How do I throw politicians in jail for blocking necessary care?

Why don't we look across the Channel and oh? What's that? A shiny sharp guillotine? Don't mind if we do

Ah yes and it was famously the politicians that showed them the light. Not other doctors conducting research and presenting evidence.

Politicians certainly never had to be dragged kicking and screaming into the 21st century of medicine.

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Oh, great. Vulnerable children and desperate parents searching for prescription medication on the black market. What could go wrong?

Mission accomplished.

Right wing conservatives can go pound sand. Talk about the government pushing itself between a doctor and patient care.

A landmark bullshit decision.

All right wingers want for Christmas is increased suicidality of anyone unlike themselves

Or probably more accurately if you look at right wing scandals, people that think similarly to them but are brave enough to live their truth and not try to hide behind a bible and pay their reality away.

Conservatives are cowards. They mainline fear 24/7, they feel list without it.

Best interest of the child my ass. I knew and know so many trans kids that suffer(ed) so much from such awful transphobic laws.
That's just purely disgusting and will have horrible consequences for so many people. I am so sorry for every trans kid in England that suffers from this. :(

40 years of Hollyweird / Music Industry / Olympics trainer agents pumping their youngest stars full of this shit in order to squeeze an extra year or two of revenue out of them? Fine. Cool. Good. No problems detected.

Some trans youth have a legitimate medical need for deferring puberty, while they come to terms with their gender and sexuality? Fuck you. Prohibited. Go directly to jail.

its almost like the weirdo hollywood guys are in league with the weirdo religious guys.

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So does this also apply to precocious puberty or is this purely a fuck you to trans people?

They're going to have to pull an Alabama and do some matching legal and mental gymnastics.

You see, every other problem in the UK has been solved, so now all they have left is fucking with people who just want to be happy in their own body.

Right-wingers pick on minorities precisely because they have no plans for how to improve life for people in general, and in fact not the slightest interest in doing so. If they were honest about that, no one would vote for them, so they have to invent scapegoats and distractions. Somehow it's easy to persuade a lot of people that some entirely made up problem is the most urgent, such as some minority coming to destroy their "way of life", and thereby distract them from all the actual problems you have caused for them.

Right wing politics is always privileged sociopaths duping the gullible and ignorant.

It's specifically for gender identity clinics so only applies to trans kids

Time to start some really large clinical trials.

Which wouldn't be a bad idea anyway, tracking long-term outcomes.

GnRH was discovered in 1971, and has been available since the '80s. We have a pretty good idea of their long term effects. There could be more about effects on transgender youth in particular, but everything done so far shows it's safe.

I'm reading about migraines, joint pain, hot flashes/sweating, decreased libido (which I would expect to take place during treatment) persisting for months after discontinuing use of GnRH. I'm also reading that it can worsen diabetes and osteoporosis?

Idk, to say that it's without risk is false I think.

Safe does not mean no side effects. Those first things would still absolutely qualify it as safe. Those last two you mention seem to be inconclusive by the way you worded it.

I word it this way because I'm not an expert, I was reading through a few studies I found on Google and am no way qualified to weigh in on this beyond a cursory glance.

That being said, I've heard migraines be described similarly to torture. We can agree to disagree as to whether or not that's safe (the effects of chronic pain are well documented).

Also

Prolonged treatment with Gonadotropin-Releasing Hormone (GnRH) agonists is known to induce bone loss among prostate cancer patients. However, evidence on the skeletal effects of GnRH antagonists is relatively less well-known. This review aims to examine the effects of GnRH antagonists on bone health. GnRH antagonists are an effective treatment for hormone-dependent conditions, such as advanced prostate cancer and endometriosis. They induce a competitive and reversible GnRH-receptor blockage, thereby suppressing the release of gonadotropins and sex hormones. The sex hormone ablation results in undesirable side effects, including accelerated bone loss. In animal studies, treatment with GnRH antagonists is reported to cause deterioration of bone microstructure. Human clinical trials revealed significant bone loss at the spine, hip and femur in patients treated with GnRH antagonists. Thus, osteoporosis and the resultant fragility fractures pose a significant impact on health and quality of life of GnRH antagonist users. Thus, early preventive measures of bone loss are critical in preventing fractures and its associated morbidity in these patients.

The abstract from this https://www.eurekaselect.com/article/112477

There are certainly other factors to consider, GnRH is used to treat prostate cancer if I'm not mistaken. I have no idea what would happen in an AFAB, and truth be told I'm not going that deep. I don't think anyone should be telling anyone what they can or can't put in/do with their bodies, but I'm not sure what to believe about the risk. Reading this would certainly make me second guess taking them considering my family history of arthritis.

🤷‍♂️ idk mane

Yeah, you don't know... It's really not what it seems though, and it's not actually about starting with a conclusion (we shouldn't be treating trans kids) and then only glomming onto whatever scraps you can find that might indicate that your worldview is correct, while simply ignoring that mountains of evidence to the contrary.

Definitely not that. You're just asking questions! And it's just a coincidence that every time someone tells you why you're wrong, or asks you for more detail about your arguments, you resort to the whole, "I don't know, I'm not an expert." Yeah no shit.

So you just didn't read the part where I said "we shouldn't be telling people what they can or can't put in their bodies", huh?

My advice to you is to stop letting your emotions dictate your words.

Edit: oh yeah, after re-reading what I wrote you definitely rage typed this response. Do better.

Do yourself a favour and don't read the possible side effects on the back of the box of paracetamol you bought from the supermarket.

Yeah I actually do my utmost to avoid taking Acetaminophen.

How many of these side effects could just be the result of starting puberty after stopping the medication?

I genuinely don't know, but is osteoporosis common as a result of puberty?

Edit:

later puberty was linked to lower bone mineral density, and that both are risk factors for osteoporosis

Also a risk when taking birth control, the question is how severe and can you recover after completing puberty.

Idk how I feel about kids taking birth control either, is that a normal thing??

If you don't want kids getting pregnant, yes.

Wait you mean they have to start taking hormonal birth control before they start having sex?

Next you’re going to tell me they should get the HPV vaccine before they start having sex too!

My point is moreso that kids shouldn't be having sex, but sure yeah. Read into it guys.

My apologies that you couldn’t get laid in high school.

...

So you're either suggesting that 12 year olds should be fucking high schoolers, or you're just too dumb to think about what you said.

I'll give you a few minutes.

I mean I don't, but more because I don't like the thought of kids having sex.

You can't stop people from having sex, so it's best to give them the education and healthcare necessary to reduce risks.

I don't disagree with that. The idea of high schoolers fucking 12 year olds will never sit well with me but sure, it's probably best they don't get pregnant as a result of it.

Ah I was referring to it as a side effect of birth control in adults. But birth control for ones that have gone through puberty is definitely better than the possibly deadly side effects of child birth and pregnancy.

It's been around since the 80s, we already know long term outcomes.

Um, excuse me, who said 40 years was long enough? If we don't have trials that show how people receiving these drugs turned out all the way until they died then we don't really have long term trials, do we?

/s

It's such a fucking cop out. Nothing will ever be good enough for some people.

I dont want to speak to the social aspect of this issue, but I have to imagine that blocking puberty has some crazy side effects. How long has this medical technology been in use and where can I find studies about it? Again, I know this is sensitive and I am just curious from a biological standpoint.

blocking puberty has some crazy side effects.

I'm a provider at a children's hospital. I specialize in orthopedics and rehabilitation, so I mostly deal with the musculoskeletal system. I have colleagues who would be able to provide a much better and more in depth explanation, but I will do my best.

Even in orthopedics "hormone blockers" are used fairly frequently. For example the same drugs that people use to transition are utilized to moderate the epiphyseal fusion of growth plates. Puberty is also frequently delayed to moderate the hormone levels of juvenile cancer patients. Or even more increasingly common, to halt the symptoms of precocious puberty in young women.

The vast majority of juveniles prescribed hormones to delay puberty are for non gender affirming care like cancer. The problem with moderating what medical providers can and can't treat is that you are assuming you know more about medicine than the a person who went to medical school.

You may be trying to protect kids, but what ends up happening is an interference of medical care, and usually not the type you intended. If hormone drugs become more monitored, providers may be hesitant, or have a more difficult brine prescribing it.

The dangers of delaying puberty are very small, when you stop the prescription puberty begins again. Usually the only side effect is excessive growth due to a delay if epiphyseal fusion. In regards to gender affirming care, I will remind people that their providers are looking at total outcomes. Meaning they are factoring in things like the higher potentiality of self harm and suicide.

Thank you for your reply! This is good information

refers to self as provider

Definitely not a doctor.

Provider is actually the preferred terminology in most hospitals nowadays. It helps transition away from physicians being the "captain of the ship" to a more team based medical approach.

It also helps boost patient confidence in the entire medical team, especially in places like where I work, where there are a lot of residents and PAs doing the bulk of the patient care.

The AMA literally says the opposite:

https://www.ama-assn.org/system/files/a-23-omss-resolution-5.pdf

The only people pushing “provider” are administrators who would prefer to muddy the waters with regards to who providers care, and the midlevels who benefit.

Lol, Idk. Do people go to medical school for the title, or to actually help people?

I like the team approach, and I think referring to everyone as a provider is especially good for my residents, some of which will occasionally think they know more than a PA-C who's been here for 30 years, just because they don't have an MD after their name.

The only doctors that care about being called doctor are residents who think too highly of themselves, or the dinosaurs who hate patient care and only got into the field for the prestige.

You can feel about it however you’d like, but the term provider was purposely used to justify different care without patients being aware.

It’s not a matter of a 30 year PA vs a resident, experience certainly matters. But I take issue when you claim medical knowledge because you’re a “provider”, and especially because you work in a pediatric hospital. The role of a pediatric endocrinologist and an ortho PA almost don’t overlap, and the background schooling almost don’t either.

That’s not to say I’m particularly qualified either (it’s outside my specialty) but you infer that you’re qualified to comment when you and I both know, frankly, you’re not.

used to justify different care without patients being aware.

Lol, you really think a PA is going to provide different care than an MD? What, an MD is going to prescribe PT and bracing when a PA is going to ...... chop their leg off?

But I take issue when you claim medical knowledge because you’re a “provider”, and especially because you work in a pediatric hospital.

Did I not predicate my statement with my lack of speciality? What exactly did I say that was false? If you have problems with the information I stated then say so. But, if all you are doing is appealing to an entirely assumed authority, go kick rocks.

The role of a pediatric endocrinologist and an ortho PA almost don’t overlap, and the background schooling almost don’t either.

What? I mean endocrinology doesn't refer the majority of our patients, but it's a significant amount..... Also, the only information I gave over endocrinology, directly pertains to my field.

but you infer that you’re qualified to comment when you and I both know, frankly, you’re not.

Lol, I have no idea how qualified you are, and you have no idea what my qualifications are. However, based on your statement I highly doubt you actually work in patient care. Seems like you're pretending to be a character of a doctor from a 00's medical drama.

I know therapists and other medical professionals. There is a push to let people see non physicians directly instead of needing a physician to refer you to the person who can obviously help you more.

Yeah really. Trust the science. Trust the doctors. NHS says it and it will be so.

Precocious puberty has been a thing forever and the first medications for delaying it by regulating hormones have been around since the 1980s. I think that should be the jumping off point for research. However afaik the same sorts of drugs are also commonly used to treat cancer in adults.

Here is an article about their use in treating trans people with links to various studies https://transfemscience.org/articles/puberty-blockers/

Thank you for the info and link! I will read up

How long has this medical technology been in use and where can I find studies about it?

Decades. It was there when I was a kid, so like 20 years ago. And it wasn't new medical technology at the time.

I have to imagine that blocking puberty has some crazy side effects.

Sort of the joke. Puberty is what has the crazy side effects.

It reduces bone density. Not to unhealthy levels in teens, but there are concerns the lower baseline will increase osteoporosis risk when the patients get to old age.

They can also only be used for a couple of years. Some non-binary people want to be on them permanently, but doctors won't prescribe that. Some kids want more time to decide, and unfortunately there isn't anything safe to use through the full teenage years.

The side effects and risks are worth it when you only get one shot at puberty. If you don't transition as a pre-pubescent teenager, you will never "pass" as well, especially as a transwoman.

A really good example of how successful you can be if you're early is Corey Maison. There are cases of transition regret of course, but they're still a very small percentage of the total, and that percentage is reduced by puberty blockers giving young people more time to figure out themselves and their own bodies, and to make the choice that's right for them.

Yeah, that's the gravity of things that people don't seem to understand. Yes, there can be unwanted side effects from puberty blockers, but they are relatively minor. On the other hand, one possible side effect for people that are willing to brave those puberty blocker side effects but aren't allowed to do so is suicide. This is unfortunately often life or death.

There's some studies that found that bone density could be affected, but considering the suicide rate of trans people I'm going to say that's a tiny sacrifice for the assurance that you can have the body your brain wants to be in.

Discovered in 1971, and introduced for medical use in the 1980s.

"Where can I find studies about it"?

Have you tried perhaps, idk, a search engine? How do I have a feeling that even if I were to show you the science which agrees that they are safe medications, you'd have an "argument" in which you criticise the info without even reading it.

People perfectly well know how to look for things online, and when they pretend not to... well, it smells fishy. Fishy, like sealions.

You seem really unpleasant. Good luck out there, friend.

You seem really pretentious.

I hope you get over that. I can give you some contacts if you need a good therapist, buddy.

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I thought quackery was illegal, but apparently not when it's *fundamentalists in politics.

*Fundamentalists as in fundamentally sociopaths.

Whoever decided this can shove a cactus up somewhere.

Fuck you for hurting the most vulnerable;
disgusting decision by disgusting people.

You might wanna rephrase your second sentence

As a non native speaker the honest question, why?

Fuck you for hurting the most vulnerable, disgusting decision by disgusting people.


Kann übersetzt werden zu:

Fickt euch dafür die verletzlichste, abscheulichste Entscheidung von abscheulischen Leuten zu verletzen. (weird weil wörtliche Übersetzung; kann auch Beschädigen o.ä. nutzen. Geht mehr um den Sinn als das Wort)


Ist vermutlich gemeint:

Fickt euch dafür die Verletzlichsten zu verletzen; Abscheulische Entscheidung abscheulicher Leute.

Ah danke, habs geändert.

That said I had to really try hard to deliberately missunderstand it.

But well, we seem to have the same native language and therefore maybe intuitively misstranslate it the same way? ^^

Another Tory L as usual.

Can’t wait till the day comes when they’re out of the gov for good.

You confident that blue Labour will reverse this policy?

Prob not tbh but since how bad everything is atm, any change at this point is better than none at this rate.

It's all part of the NHS War On Mental Health. The plan is remove treatments that conservatives don't believe in because they can't see them. They will take those savings and use them to extend the lives of terminally ill people in persistent vegetative states because life is sacred and needs to be protracted and painful.

Just when I though the UK couldn't disappoint any further.

I wonder what the statistics are of "trans youth" figuring out they're actually not trans as they get older.

I was going to downvote and move on, but instead...

I have family and friends that are trans, so I have been able to kind of follow their outcomes over the years.

  1. Human gender identity and sexuality does seem to fluctuate somewhat, but it doesn't seem to me to be random. Some people fully identify as one gender but like to perform as a different one. Other people don't vary at all. In cases where people "change their mind", it's usually because they get discouraged about being able to successfully transition, or they experience severe harassment/workplace discrimination. Just in my anecdotal experience, it's never because they just randomly decide they no longer want to be trans

  2. No one is getting permanent gender affirmation treatment until they are old enough to know and have been in discussions with doctors for years. I'm sure there are exceptions where some poor 5 year olds parent(s) treated them without medical oversight but it's not common and no one wants this.

I'm assuming you're asking in good faith. I found this type of question to be especially controversial due to the legislation against gender-affirming care, especially puberty blockers. In researching further:

As others have stated, cases where permanent gender-affirming care was given, such as HRT (hormone therapy) and GRS (genital reconfiguration surgery), instances of regret are incredibly rare, and almost always predicated by lack of support for the individual. They are far outnumbered by instances of trans people undergoing puberty incompatible with their gender, which is itself damaging and irreversible.

The type of care discussed in this article, GnRH (puberty blockers), has been shown to not have long term consequences, and is only used to delay puberty and the potential long term effects, giving them enough time to make an informed decision about their transition. From the Mayo Clinic:

GnRH analogues don't cause permanent physical changes. Instead, they pause puberty. That offers a chance to explore gender identity. It also gives youth and their families time to plan for the psychological, medical, developmental, social and legal issues that may lie ahead..

When a person stops taking GnRH analogues, puberty starts again.

Extremely uncommon. But on the off chance it happens, they just stop taking the puberty blockers and everything proceeds as normal.

Basically non-existant but of course when it does happen it gets repeated over and over again. The main reason why anybody detransitions is because of how they get treated during their transition.

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Great Britain should be renamed as Terf Island. Make it descriptive.

Nah, they prefer prescriptivism. Actually, Terf Island still makes sense from that lens.

I'm not sure, but there's a descriptivism/prescriptivism joke in there somewhere.

Right wing twats trying their best to destroy as many children as they can

We know so little about the actual process of gender dysphoria. Hormone blockers don't solve or fix anything, but have been used simply because it's the only thing that does something. Essentially bringing a blunt instrument to the problem.

Considering the harmful nature of hormone blockers, I'm for not prescribing puberty blockers to youth. However, only so long as more research is put into it.

Can you point me to the harmful nature of them?

Hormone blockers are generally used because it's far easier for people to transition if they haven't already been smacked around by puberty and it ends up giving a healthier result.

https://www.texastribune.org/2023/03/24/texas-transgender-kids-transition-related-health-care/

(I KNOW, right? "Texas Tribune?")

"Studies have found that transgender youth who take puberty blockers are significantly less likely to experience lifelong suicidal ideation than those who want the care and don’t get it. And studies show psychological trauma is reduced and life satisfaction increases when people who want transition-related hormone therapy get it.

Major medical associations support transition-related care. They include the American Academy of Pediatrics, the American Medical Association, the Endocrine Society, the World Medical Association and the World Professional Association for Transgender Health."